Best 10 Audio Interfaces With MIDI Input And Output For 2026

If you need clean audio capture and reliable MIDI connectivity in one box, this roundup is built for you. The best audio interfaces with midi input and output can simplify your setup while keeping latency low and workflow flexible.

Below, we focus on models that make sense for musicians, podcasters, streamers, and small studios looking for practical I/O, dependable drivers, and useful software bundles.

Best 10 Audio Interfaces with Midi Input and Output Picks for 2026

Creator Hub Pick – Focusrite Scarlett 4i4 4th Gen

If you want audio interfaces with midi input and output for a compact studio setup, the Focusrite Scarlett 4i4 4th Gen is built to cover a lot of bases. It gives you 4-in/4-out connectivity, two mic preamps, two Hi-Z inputs, four line inputs, and MIDI I/O, so it can handle vocals, guitars, and external gear without feeling limited.

Best For: Musicians, songwriters, and content creators who want a flexible 4-in/4-out interface with MIDI and strong recording features.

Pros:

• Includes MIDI in/out plus 4 line inputs and 4 line outputs for more routing options.
• Two 4th Gen mic preamps, Auto Gain, Clip Safe, and Air mode support easier, cleaner takes.
• Up to 24-bit/192kHz recording with a 120dB dynamic range for studio-quality sound.
• Ships with Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion software.

Cons:

• More elaborate than a basic 2-channel interface if you only need simple recording.
• Requires USB-C power supply included in the box for full operation.

This is the most feature-rich option here for smaller studios that need both audio and MIDI connectivity. It is especially appealing if you want modern convenience features alongside enough I/O to grow into.

Portable Value Pick – PreSonus AudioBox 96 25th Anniversary

For buyers comparing audio interfaces with midi input and output on a budget, the PreSonus AudioBox 96 is a straightforward 2-channel choice. It offers two Class-A mic preamps, two instrument inputs, MIDI I/O, and bus-powered USB 2.0 operation, making it easy to use for portable recording sessions.

Best For: Home recordists and mobile musicians who want an affordable, bus-powered interface with MIDI.

Pros:

• 2 mic preamps, 2 instrument inputs, and MIDI I/O in a compact 2-channel design.
• Bus-powered USB 2.0 setup keeps it simple for travel and mobile use.
• Up to 24-bit/96kHz recording with balanced TRS outputs and a headphone output.
• Includes Studio One Artist, Ableton Live Lite, and Studio Magic Plug-In Suite.

Cons:

• Only 2 channels, so it is less expandable than larger interfaces.
• Max sample rate tops out at 96kHz, below some higher-end options.

This is a practical pick if you want essential recording features without paying for extra complexity. It is best when portability, MIDI support, and bundled software matter more than expansion.

DSP Monitoring Pick – Yamaha URX22C

The Yamaha URX22C is a strong choice if you need audio interfaces with midi input and output plus low-latency monitoring tools. It combines 2-in/2-out USB-C connectivity, MIDI I/O, Class-A D-PRE mic preamps, and onboard DSP-powered effects for recording and monitoring with less delay.

Best For: Players and home studios that want MIDI I/O and latency-free monitoring with built-in effects.

Pros:

• 2 combo inputs, 2 main outputs, and MIDI I/O in a rugged full-metal housing.
• 32-bit/192kHz support with DSP-powered monitoring and effects.
• Includes REV-X reverb, Channel Strip, and Guitar Amp Classics processing.
• Cross-platform support for Windows, macOS, and iOS with Steinberg software included.

Cons:

• Only 2 analog inputs, so it is not meant for larger multi-mic sessions.
• Feature set is focused on monitoring and recording rather than maximum channel count.

This interface stands out if you want practical MIDI support and hardware-style monitoring tools in one compact unit. It fits well for players who value clean recording plus effects you can hear while tracking.

Expansion Workhorse – Behringer UMC1820

If you need audio interfaces with midi input and output for a larger recording setup, the Behringer UMC1820 is designed for scale. It offers 18 inputs and 20 outputs, MIDI I/O, ADAT I/O, and eight MIDAS-designed mic preamps, giving you room for microphones, instruments, and more advanced routing.

Best For: Larger home studios and project studios that need plenty of I/O plus MIDI.

Pros:

• 18×20 audio/MIDI interface with ADAT I/O for expanded connectivity.
• Eight MIDAS-designed mic preamps with +48V phantom power.
• Up to 24-bit/96kHz audio quality and ultra-low latency streaming.
• Compatible with major recording software including Pro Tools, Ableton Live, and Cubase.

Cons:

• Much larger than a simple desktop interface and better suited to fixed setups.
• Maximum sample rate is 96kHz, which is lower than some newer interfaces.

This model makes the most sense when you need quantity and expansion more than a minimalist footprint. It is a practical centerpiece for studios that want lots of I/O and built-in MIDI support.

Compact Starter Pick – M-AUDIO M-Track Duo USB Audio Interface

If you’re comparing audio interfaces with midi input and output for a simple recording setup, the M-AUDIO M-Track Duo is a compact USB interface aimed at everyday podcasting, streaming, and basic music recording. It focuses on straightforward input options, low-latency monitoring, and included software rather than extra hardware features.

Best For: Beginner creators who want a portable interface for vocals, guitar, and general home recording.

Pros:

• Two combo XLR/line/instrument inputs with phantom power for mics and instruments.
• 48kHz recording resolution and transparent Crystal Preamps for clean capture.
• USB/direct monitoring switch plus 1/4" headphone and stereo outputs for flexible monitoring.
• Includes MPC Beats software to help you start recording right away.

Cons:

• No MIDI I/O is listed in the supplied product details.
• Limited to 2 channels, so it is not built for larger setups.
• Maximum sample rate is 48kHz, which is lower than some competing interfaces.

This is a practical entry-level interface if you value portability and simple operation over advanced connectivity. It covers the basics well for solo recording, but buyers specifically needing MIDI input and output should look elsewhere.

Best MIDI-Ready Workhorse – Behringer U-PHORIA UMC404HD

Among audio interfaces with midi input and output, the Behringer U-PHORIA UMC404HD stands out as a true USB audio/MIDI interface with 4×4 connectivity and 24-bit/192 kHz resolution. It is built for users who need more routing flexibility, multiple inputs, and dedicated MIDI I/O for recording instruments and integrating external gear.

Best For: Musicians and producers who need a budget-friendly 4×4 interface with MIDI connectivity.

Pros:

• Includes 1x MIDI I/O alongside 4 inputs and 4 outputs.
• 24-bit/192 kHz audio quality for high-resolution recording.
• Four MIDAS-designed mic preamps with +48V phantom power.
• Metal chassis and low-latency USB 2.0 operation for a sturdy desktop setup.

Cons:

• Heavier and larger than compact 2-channel interfaces.
• Compatibility notes are centered on older Windows systems in the supplied details.
• No bundled software is highlighted in the provided notes.

If MIDI support is a must-have, this is the strongest fit in the lineup because it clearly adds MIDI I/O without giving up multi-channel audio. It makes the most sense for home studios that want a durable interface with room to grow.

Creator Routing Pick – MAONO P1 USB Audio Interface

If you want audio interfaces with midi input and output for creator-focused recording, the MAONO P1 is worth a look for its hybrid connectivity and routing tools. The supplied notes emphasize dual USB ports, loopback, auto gain, and software-based channel routing for podcasting, streaming, and mobile music recording.

Best For: Streamers and solo creators who want flexible phone-and-computer recording with simple routing controls.

Pros:

• Dual USB ports with MFi-certified connectivity for computer and phone or iPad workflows.
• Up to 70dB gain and 24-bit/192kHz recording for demanding microphones.
• Auto-Gain, loopback, and ProStudio2 routing software simplify streaming setups.
• Direct monitoring and independent headphone/monitor mute controls add flexibility.

Cons:

• No MIDI input or output is listed in the provided product details.
• Primarily geared toward solo creator workflows rather than multi-instrument studio rigs.
• Detailed I/O count beyond creator-routing features is not fully specified in the notes.

The P1 is a strong choice if your priority is easy routing, mobile compatibility, and creator-friendly controls. It is less compelling for buyers whose main requirement is confirmed MIDI I/O.

Starter Singer/Creator Pick – Scarlett Solo 3rd Gen

If you want one of the simplest audio interfaces with midi input and output alternatives in a compact USB format, the Focusrite Scarlett Solo 3rd Gen is a strong entry-level choice for guitarists, vocalists, and podcasters. It focuses on clean recording, straightforward monitoring, and the included software bundle so you can start tracking music quickly.

Best For: Solo artists who want an easy-to-use interface for vocals and guitar recording.

Pros:

• 1 XLR mic preamp plus 1 Hi-Z instrument input for basic vocal and guitar setups
• 24-bit/192kHz recording with Focusrite’s high-performance converters
• Air mode adds extra clarity to acoustic instruments
• Includes Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion

Cons:

• Only one mic preamp and one instrument input
• Not a fit if you need multiple simultaneous inputs
• No MIDI ports listed in the supplied specifications

Overall, the Solo 3rd Gen is best when your priority is reliable, studio-quality recording in a very simple format. It is not the model to choose for MIDI hardware routing, but it is a practical low-friction interface for basic tracking and playback.

Best All-Round Home Studio – Scarlett 2i2 4th Gen

For buyers comparing audio interfaces with midi input and output features, the Focusrite Scarlett 2i2 4th Gen is a versatile USB option for recording, songwriting, streaming, and podcasting. It gives you two mic preamps, two Hi-Z inputs, and updated auto-level tools that make it easier to capture clean takes without constant gain tweaking.

Best For: Creators who want a flexible two-input interface with modern recording features.

Pros:

• 2 mic preamps and 2 Hi-Z instrument inputs for more flexible sessions
• 120dB dynamic range and converters used in Focusrite’s flagship interfaces
• Auto Gain and Clip Safe help prevent bad levels and clipping
• Air modes add presence and harmonic drive to vocals and guitars

Cons:

• Still limited to two channels
• Supplied details do not list dedicated MIDI ports
• Best suited to small setups rather than larger multi-input rigs

The 2i2 4th Gen stands out for people who want a polished, modern interface with strong recording aids and broad compatibility. It is a smart pick for a compact studio setup, though MIDI gear users should confirm their routing needs separately.

Compact Solo Creator Choice – Scarlett Solo 4th Gen

If you are shopping for audio interfaces with midi input and output support but mainly need a compact USB interface for recording vocals and guitar, the Focusrite Scarlett Solo 4th Gen is a straightforward option. It keeps the setup simple while adding the upgraded 4th Gen sound and useful recording features for singer-songwriters.

Best For: Solo creators who want a small interface with strong vocal and guitar recording quality.

Pros:

• 1 XLR mic preamp and 1 Hi-Z instrument input for simple tracking
• 120dB dynamic range for studio-quality recording
• Improved Air mode adds presence and harmonic drive
• Includes Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion

Cons:

• Only one mic input and one instrument input
• Not intended for multi-source recording setups
• No MIDI connectivity is listed in the supplied details

The Solo 4th Gen is best viewed as a streamlined writing and tracking interface rather than a control hub. It delivers the clean, modern Scarlett sound in a very compact package, but it is not the right match if MIDI I/O is a must-have.

How We Picked These Audio Interfaces with Midi Input and Output

We prioritized interfaces that offer a sensible balance of sound quality, driver stability, MIDI support, input/output flexibility, and value. We also considered whether the interface is easy to use for beginners, expandable enough for growing setups, and suitable for common tasks like tracking vocals, recording guitar, streaming, and sequencing external gear.

Quick Comparison

Among Audio Interfaces with Midi Input and Output, smaller 2-in/2-out models are usually best for solo creators, while 4-channel and higher-channel units better serve drum machines, synth rigs, and compact band recording. USB-C and higher-resolution converters can improve modern workflow, but the right choice still depends on how many sources you record at once and whether you need extra routing features.

Key Buying Factors for Audio Interfaces with Midi Input and Output

Channel Count and I/O

Choose the number of mic, line, and instrument inputs you actually need now, plus a little headroom for future gear. If you use outboard synths, controllers, or drum machines, make sure the MIDI ports are paired with enough analog inputs to capture everything cleanly.

Preamps, Gain, and Noise Performance

Good preamps matter more than flashy specs. Look for enough clean gain for dynamic microphones and quiet performance at higher levels, especially if you record vocals or quieter acoustic sources.

Monitoring, Loopback, and DSP

Direct monitoring helps you record without distracting delay. Loopback is useful for streaming and podcasting, while onboard DSP can add convenience for monitoring effects or low-latency processing.

Compatibility and Software

Check OS support, included drivers, and bundled software before buying. Some interfaces are better optimized for Windows, others for Mac, and not every package includes the recording tools you may want.

Who Should Buy Which Audio Interfaces with Midi Input and Output?

If you are a singer-songwriter or solo producer, a compact 2-channel interface is usually the most practical choice. If you need to integrate external MIDI gear or track multiple sources at once, step up to a 4×4 or larger model. Streamers and podcasters should put extra weight on loopback, monitoring controls, and microphone gain. Home studio users who plan to expand later should favor Audio Interfaces with Midi Input and Output that offer stronger routing, better expandability, and room to grow.